Author Information

Timothy E. O'Brien

Abstract

This paper discusses model and experimental design aspects of agricultural studies aimed at discerning antagonism or synergy between two or more insecticides, herbicides, or other similar compounds. The developed methods involve a broad class of generalised nonlinear models, which are easily fitted to data using popular statistical packages such as the NLMIXED procedure in SAS® software. Sample computer code is given in the Appendix.

Keywords

antagonism, combination index, experimental design, generalized nonlinear models, isobolograms, optimal design, phenolic acids, synergy

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Apr 27th, 5:00 PM

MODELING AND DESIGN TO DETECT INTERACTION OF INSECTICIDES, HERBICIDES AND OTHER SIMILAR COMPOUNDS

This paper discusses model and experimental design aspects of agricultural studies aimed at discerning antagonism or synergy between two or more insecticides, herbicides, or other similar compounds. The developed methods involve a broad class of generalised nonlinear models, which are easily fitted to data using popular statistical packages such as the NLMIXED procedure in SAS® software. Sample computer code is given in the Appendix.