A putative homolog of the Sacharromyces cereviseae ADE6 and Escherichia coli purL genes is identified near a multigenic complex, which contains two genes, sid1 and sid2, involved in a siderophore biosynthetic pathway inUstilago maydis. The putative ADE6 homolog was mutated by targeted gene disruption. The resulting mutant strains demonstrated a requirement for exogenous adenine, indicating that the U. maydis ade6 homolog is required for purine biosynthesis.
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Heidenreich, M. L.,
"Disruption of a Yeast ADE6 Gene Homolog in Ustilago maydis,"
Fungal Genetics Reports:
Vol. 55, Article 10.