betaine, guanidinoacetic acid, growing cattle
Objective: This study was conducted to evaluate effects of guanidinoacetic acid and creatine supplementation in the presence or absence of supplemental betaine on lean tissue growth in growing cattle.
Study Description: Seven ruminally cannulated Holstein steers (417 lb) were used in an experiment where each steer received each of six treatments. The first treatment set was conducted via abomasal infusion of a saline solution (control), 15 g/day guanidinoacetic acid (GAA), or 16.8 g/day creatine, and the second set was conducted via abomasal infusion of 0 or 5.6 g/day betaine; all treatment combinations were represented. Complete collection of urine and feces was used to determine nitrogen retention as a measure of protein deposition. Steers were limit-fed a corn-based diet similar to that of a production-type setting.
Bottom line: Supplementing 5.6 g/day betaine increased lean tissue growth in growing steers fed corn-based diets.
Grant, M. S.; Marsh, J. M.; Hazlewood, K. J.; Miesner, M. D.; and Titgemeyer, E. C.
"Effects of Betaine on Protein Deposition in Growing Cattle with Modulated Methyl Group Status,"
Kansas Agricultural Experiment Station Research Reports: