Abstract
The subject of multiple comparisons has early roots in statistical methods that were applied in agricultural sciences, often using simple methods with questionable properties popularized by no less than R.A. Fisher. More recently, problems of multiple comparisons have surfaced in the pharmaceutical sciences. In the extremely competitive and highly regulated pharmaceutical environment, it has become essential to take multiple comparisons more seriously, and to use more sophisticated methods. In this paper I describe the need for considering multiple comparisons, with special reference to the recent shift in approach to multiple comparisons in the pharmaceutical industry. I also offer speculations about the effect of this shift on how multiple comparisons will come to be viewed the 21 st. century.
Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 License.
Recommended Citation
Westfall, Peter H.
(2001).
"FROM FARMS TO PHARMACEUTICALS: MULTIPLE COMPARISONS ENTERS THE 21ST CENTURY,"
Conference on Applied Statistics in Agriculture.
https://doi.org/10.4148/2475-7772.1212
FROM FARMS TO PHARMACEUTICALS: MULTIPLE COMPARISONS ENTERS THE 21ST CENTURY
The subject of multiple comparisons has early roots in statistical methods that were applied in agricultural sciences, often using simple methods with questionable properties popularized by no less than R.A. Fisher. More recently, problems of multiple comparisons have surfaced in the pharmaceutical sciences. In the extremely competitive and highly regulated pharmaceutical environment, it has become essential to take multiple comparisons more seriously, and to use more sophisticated methods. In this paper I describe the need for considering multiple comparisons, with special reference to the recent shift in approach to multiple comparisons in the pharmaceutical industry. I also offer speculations about the effect of this shift on how multiple comparisons will come to be viewed the 21 st. century.
