Article Title
Keywords
Cattlemen's Day, 1975; Report of progress (Kansas State University. Agricultural Experiment Station); 230; Beef; Polioencephalomalacia; Thiamin
Abstract
In ruminants fed high grain rations, a condition called polioencephalomalacia (PEM), characterized by central nervous system derangement, can develop. It usually is noninfectious, responds to thiamin injections, and is characterized by sudden onset. Using artificial rumen techniques, we established that PEM results from a bacteria-produced enzyme in the rumen that converts the vitamin thiamin to a nonusable alternate form, pyrithiamin, which in turn caused severe metabolic disturbances in the central nervous system.
First page
64
Last page
66
Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.
Recommended Citation
Sapienza, D.A. and Brent, B.E.
(1975)
"Polioencephalomalacia (PEM)-Current research status,"
Kansas Agricultural Experiment Station Research Reports:
Vol. 0:
Iss.
1.
https://doi.org/10.4148/2378-5977.2751
